Holdsworth Retrofit and Renovation

The University of Massachusetts has a rapidly evolving commitment to reducing greenhouse gas emissions and improving the environmental sustainability of its operations. According to the most recent IPCC report, the buildings sector has more potential to contribute to climate change mitigation than any other sector.1 The energy efficient designs of the current spate of building projects are indicative of the University’s commitment to green building—reducing the energy intensity of the university relative to building area and activities. However, these efforts cannot reduce the total energy use or greenhouse gas emissions from current levels. Among the University’s assets with the greatest potential to achieve these goals are its existing buildings. Most of these are good buildings that have not reached the end of their useful life. Forty-two buildings, encompassing more than half of the general administration and educational space fall into the categories of “catch up and keep up” or “keep and renew” according to the university’s Building Disposition Report.2 Many of the existing buildings have great historical, aesthetic, and emotional value and have stood the test of time as the site of the academic, scientific, and cultural work that is their primary purpose. Can these buildings be updated to dramatically reduce their energy consumption and allow them to continue to function as valuable assets for the long term? What levels of energy savings are possible and reasonable? This report is designed to answer these questions for one representative building: Holdsworth Hall. The recommendations in this report are the product of a detailed and careful examination and exploration of the building and its operations. The investigations and proposed solutions are motivated by two principles: First, the architectural intention should be respected. The building as designed works well on many levels, and no recommendation should undermine currently effective systems and designs or compromise the aesthetic intention of its designers. Second, the building is a complex system, and no change can be considered in isolation. Single measures may achieve savings, but cannot maximize savings or performance without complementary changes in related systems. A final package of recommended measures will define a new building system with emergent properties that make for a qualitatively different and better building beyond simple energy consumption metrics. 1

Disc-Jet coupling in the LMXB 4U1636-53 from INTEGRAL

We report on the spectral analysis results of the neutron star, atoll type, low mass X-ray Binary 4U1636-53 observed by INTEGRAL and BeppoSAX satellites. Spectral behavior in three different epochs corresponding to three different spectral states has been deeply investigated. Two data set spectra show a continuum well described by one or two soft blackbody plus a Comptonized components with changes in the Comptonizing electrons and black body temperature and the accretion rates, which are typical of the spectral transitions from high to low state. In one occasion INTEGRAL spectrum shows, for first time in this source, a hard tail dominating the emission above 30 keV. The total spectrum is fitted as the sum of a Comptonized component similar to soft state and a power-law component (Gamma=2.76), indicating the presence of a non thermal electron distribution of velocities. In this case, a comparison with hard tails detected in soft states from neutron stars systems and some black hole binaries suggests that a similar mechanism could originate these components in both cases.Comment: 6 pages, 4 figures, 2 tables. accepted Ap

Precautionary labelling of foods for allergen content: are we ready for a global framework?

© 2014 Allen et al.; licensee BioMed Central Ltd.Food allergy appears to be on the rise with the current mainstay of treatment centred on allergen avoidance. Mandatory allergen labelling has improved the safety of food for allergic consumers. However an additional form of voluntary labelling (termed precautionary allergen labelling) has evolved on a wide range of packaged goods, in a bid by manufacturers to minimise risk to customers, and the negative impact on business that might result from exposure to trace amounts of food allergen present during cross-contamination during production. This has resulted in near ubiquitous utilisation of a multitude of different precautionary allergen labels with subsequent confusion amongst many consumers as to their significance. The global nature of food production and manufacturing makes harmonisation of allergen labelling regulations across the world a matter of increasing importance. Addressing inconsistencies across countries with regards to labelling legislation, as well as improvement or even banning of precautionary allergy labelling are both likely to be significant steps forward in improved food safety for allergic families. This article outlines the current status of allergen labelling legislation around the world and reviews the value of current existing precautionary allergen labelling for the allergic consumer. We strongly urge for an international framework to be considered to help roadmap a solution to the weaknesses of the current systems, and discuss the role of legislation in facilitating this

Effect of Nedocromil Sodium on Aspecific Bronchial Hyper-Reactivity in Asthmatic Children

The purpose of this study was to evaluate whether nedocromil sodium benefits urban asthmatic children showing seasonal bronchial hyper-reactivity to ultrasonic nebulization of distilled water (UNDW). A prospective, randomized, placebo-controlled, parallel-group, double-blind study was carried out at the outpatient pulmonology service at a tertiary-care teaching hospital. Twelve children living in Milan, who were 7–17 years of age, who were SPT and RAST-negative to perennial allergens, who were suffering from episodic asthma, and showing seasonal bronchial hyper-reactivity to UNDW during winter, participated in this study. All the children received either placebo or nedocromil sodium, 4 mg every 6 h for 6 weeks. Spirometry and UNDW challenge were done at the following times: day−7; day 0; day 1; day 7; day 14; day 28; day 42. No differences were found in the basal spirometric parameters, which were normal in both nedocromil and placebo groups. Bronchial reactivity to UNDW was found to be significantly decreased in the group treated with nedocromtl starting from day 7. It is therefore concluded that nedocromil sodium can reverse bronchial hyper-reactivity caused by seasonal factors such as cold, viral infections and atmospheric pollutants in children suffering from asthma

Swift-XRT observation of 34 new INTEGRAL/IBIS AGNs: discovery of Compton thick and other peculiar sources

For a significant number of the sources detected at high energies (>10 keV) by the INTEGRAL/IBIS and Swift/BAT instruments there is either a lack information about them in the 2-10 keV range or they are totally unidentified. Herein, we report on a sample of 34 IBIS AGN or AGN candidate objects for which there is X-ray data in the Swift/XRT archive. Thanks to these X-ray follow up observations, the identification of the gamma ray emitters has been possible and the spectral shape in terms of photon index and absorption has been evaluated for the first time for the majority of our sample sources. The sample, enlarged to include 4 more AGN already discussed in the literature, has been used to provide photon index and column density distribution. We obtain a mean value of 1.88 with a dispersion of 0.12, i.e. typical of an AGN sample. Sixteen objects (47%) have column densities in excess of 10^{22} cm^{-2} and, as expected, a large fraction of the absorbed sources are within the Sey 2 sample. We have provided a new diagnostic tool (NH versus F(2-10)keV/F(20-100)keV softness ratio) to isolate peculiar objects; we find at least one absorbed Sey 1 galaxy, 3 Compton thick AGN candidates; and one secure example of a "true" type 2 AGN. Within the sample of 10 still unidentified objects, 3 are almost certainly AGN of type 2; 3 to 4 have spectral slopes typical of AGN; and two are located high on the galactic plane and are strong enough radio emitters so that can be considered good AGN candidates.Comment: 15 pages, 5 figures, ApJ accepte

Effect of laser welding on the mechanical and degradation behaviour of Fe-20Mn-0.6C bioabsorbable alloy

Abstract The present work aims at exploring the influence of laser welding on the functional behaviour of a Fe-20Mn-0.6C (wt.%) bioabsorbable alloy. At first, the selection of the most suitable process speed (40 mm/s) was done in order to obtain a full penetration joint with limited taper. Then, microstructural and mechanical analyses of welded sheets confirmed suitable performance of the joint, without porosity, thus preserving chemical composition, mechanical resistance and ductility even after welding. In particular, the base material comprised both γ austenite and e martensite, while the welded samples showed a further type of martensite, namely α'. Moreover, ultimate tensile strength (1095 MPa and 1104 MPa in base and welded material, respectively) and elongation to failure (61.3% and 60.9%, respectively) were almost not influenced by the welding process. Considering the absorbable nature of these alloys, static immersion degradation tests were carried out, and confirmed that the surface of the welded bead did not exhibit a significant variation of the material degradation rate after 14 days in modified Hanks' solution. Finally, a significant accumulation of degradation products, mainly (Fe,Mn)CO3, was observed along the joining line

An active state of the BL Lac Object Markarian 421 detected by INTEGRAL in April 2013

Multiwavelength variability of blazars offers indirect insight into their powerful engines and on the mechanisms through which energy is propagated from the centre down the jet. The BL Lac object Mkn 421 is a TeV emitter, a bright blazar at all wavelengths, and therefore an excellent target for variability studies. Mkn 421 was observed by INTEGRAL and Fermi-LAT in an active state on 16-21 April 2013. Well sampled optical, soft, and hard X-ray light curves show the presence of two flares. The average flux in the 20-100 keV range is 9.1e-11 erg/s/cm2 (~4.5 mCrab) and the nuclear average apparent magnitude, corrected for Galactic extinction, is V ~12.2. In the time-resolved X-ray spectra (3.5-60 keV), which are described by broken power laws and, marginally better, by log-parabolic laws, we see a hardening that correlates with flux increase, as expected in refreshed energy injections in a population of electrons that later cool via synchrotron radiation. The hardness ratios between the JEM-X fluxes in two different bands and between the JEM-X and IBIS/ISGRI fluxes confirm this trend. During the observation, the variability level increases monotonically from the optical to the hard X-rays, while the large LAT errors do not allow a significant assessment of the MeV-GeV variability. The cross-correlation analysis during the onset of the most prominent flare suggests a monotonically increasing delay of the lower frequency emission with respect to that at higher frequency, with a maximum time-lag of about 70 minutes, that is however not well constrained. The spectral energy distributions from the optical to the TeV domain are satisfactorily described by homogeneous models of blazar emission based on synchrotron radiation and synchrotron self-Compton scattering, except in the state corresponding to the LAT softest spectrum and highest flux.Comment: 11 pages, 6 figures, in press in A&